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MISSION STATEMENT

Sbarro Health Research Organization conducts research in cancer, diabetes, and cardiovascular disease. Based in Philadelphia, Pennsylvania on the campus of Temple University, our programs train young scientists from around the globe.



SALUTE PRESS NEWS

His Excellency Claudio Bisogniero, Italian Ambassador to the United States, will visit Temple's Sbarro Institute for Cancer Research and Molecular Medicine

May 16th, 2013

On Friday, May 17, 2013, at 10:30 AM, His Excellency Claudio Bisogniero, Italian Ambassador to the United States will visit Temple to honor the excellence in American-Italian research collaboration as exemplified by the Sbarro Institute at Temple. He will be joined in his tour by Temple President Neil Theobold, Provost Hai-Lung Dai, College of Science and Technology Dean Michael Klein and Sbarro Director Antonio Giordano.

For more information please see this Temple News Release .

ItalianAmbassador.pdf

The Power of Cocoa Polyphenols Against Neurodegenerative Diseases

April 11th, 2013

Epidemiological studies have indicated that dietary habits and antioxidants from diet can influence the incidence of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Now, a new study from the Sbarro Health Research Organization (SHRO), Center for Biotechnology, Temple University, Philadelphia PA and Lombardi Cancer Center , Georgetown University Washington DC (USA) , University of University of L'Aquila (Italy) and University of Siena (Italy) shows that cocoa polyphenols triggers neuroprotection by activating BDNF survival pathway, both on Aβ plaque treated cells and on Aβ oligomers treated cells, resulting in the counteraction of neurite dystrophy,

For more information please see this Newswise article .

Important International Study on the Link Between Obesity and Breast Cancer

April 3rd, 2013

The link between obesity and cancer seems now well established although the molecular mechanisms underlying this connection are still largely unexplored. A group of researchers in Italy led by Antonio Giordano, M.D., Ph.D., the Founder and Director of the Sbarro Institute for Cancer Research and Molecular Medicine, and Center of Biotechnology, College of Science and Technology of the Temple University in Philadelphia, has studied the correlation between breast cancer and insulin resistance - an obesity-related condition in which certain cells fail to respond to the glucose-lowering action of the insulin hormone.

Their findings appear in the Journal of Experimental and Clinical Cancer Research.

For more information please see this Newswise article .

Pfizer CDK Inhibitor and Cancer Progression

March 16th, 2013

Data from a recent clinical study by Pfiezer has renewed interest in CDK inhibitors to block the progress of Cancer. The concept was featured in a Nature Biotechnology article. "The main issue is to understand which CDKs should be targeted in specific cancers where they have a key role in the oncogenic process" stated Dr. Antonio Giordano of the Sbarro Institute for Cancer Research and Molecular Medicine, Temple University in Philadelphia. Dr. Giordano was the first to discover CDK9 and to describe a link between cyclins/CDKs and tumorigenesis.

For more information please see this article .

Increased Incidence of Breast Cancer in Italy

November 30th, 2012

A new study on the incidence of breast cancer in Italy has been published in the International Journal of Experimental and Clinical Cancer Research. The authors belong to a multidisciplinary Italian-American team led by Prof. Antonio Giordano, Director of the Sbarro Institute for Cancer Research and Molecular Medicine College of Science and Technology Temple University of Philadelphia, USA.

"Cancer is also a matter of numbers," says Giordano, internationally renowned oncologist engaged for years in the fight against cancer, who recently launched an appeal - signed by over 500 researchers - to protect the environment from the irresponsible dumping of toxic wastes, carcinogenic waste. "The identification of the precise number of cancer cases at a population level and by geographical area is crucial to orient public health strategies towards cancer prevention and early diagnosis."

SHRO Press Release
For more information please see the interview with Dr. Giordano and this article .

Dr. Giordano receives International Award

November 13th, 2012

Antonio Giordano, M.D., Ph.D. is being awarded the Grande Ippocrate Award for Scientific Research and Communication. The award ceremony will take place at the "Castel Nuovo"on November 19, 2012.
More Details       Conference Program      

Conference on Breast Cancer: Bridging Research and Clinical Medicine

October 6th, 2012

On October 12, 2012, from 2:00 to 4:00 p.m., the Sbarro Health Research Organization, Inc. (S.H.R.O.), the Giovan Giacomo Giordano Foundation, the College of Science and Technology at Temple University and the National Italian American Foundation (NIAF) (www.niaf.org) will jointly present the "Conference on Breast Cancer: Bridging Research and Clinical Medicine" on the occasion of NIAF's 37th anniversary gala weekend at the Hilton Hotel in Washington, D.C.
SHRO Press Release       Conference Details      

Toxic Dumping in Naples Leads to Increased Cancer Rates in Naples

August 21st, 2012

On July the 30th, the Pascale National Cancer Institute of Naples made a shocking report: 47% more people are stricken with cancer in Naples than in the rest of the Italy.
SHRO Press Release

New Properties of Stem Cells via Simulated Microgravity

July 5th, 2012

A recent study led by Andrew Puca, Ph.D. under the supervision and direction of Antonio Giordano, M.D., Ph.D. set out to illustrate novel mechanical transduction properties of Hematopoietic Stem Cells in relation to defining the expression of humoral factors by facilitating paracrine/autocrine signalling via microgravity.
PubMed   Rest of NewsWise Press Release

S.H.R.O. hosts free seminar on commercialization of science.

June 1, 2012

S.H.R.O., in collaboration with Temple University's College of Science & Technology, the Italian Trade Commission and Innova Consulting Group, will host a seminar that aims to provide concrete tools and examples to support the commercialization of science research by creating start-ups.
Flyer   Invitation

"The Price of a False Idea about Economic Growth: Health Research Cuts and Uncontrolled Toxic Agents"

May 9, 2012

In this new essay, Philosopher Sheldon W. Samuels takes us to the heart of the budget and regulatory battles that engulf the courts, congress and administration to explain the long history resulting in the sidelining of disease prevention and obstruction in controlling environmental threats to human life.

Novel Mechanism May Lead to New Targeted Pharmacological Cancer Treatment

April 24, 2012

In a new study from the Sbarro Health Research Organization, Flavio Rizzolio shows that Pin1 (protein interacting with NIMA (never in mitosis A)-1), a peptidylprolyl isomerase involved in the control of protein phosphorylation, is an essential mediator for inactivation of the pRB. The findings, published in Cell Death and Differentiation, have important implications for cancer treatment.
Temple News Release   Abstract in PubMed

Eight Rules For Living better

March 28, 2012

This article, published in Italian in the online journal La Gazzetta Gastronomica, outlines eight simple rules that the World Cancer Research Fund recommends for achieving a healthy lifestyle.

Italy's Eco Mafia. Mafia Are Cashing In On Toxic Dumping and Other Environmental Crimes.

March 28, 2012

Christine MacDonald's article published in E Magazine (March/April 2012) discusses how the Mafia has continued to commit atrocious environmental crimes (more than 30,000 in 2010 in Italy alone, according to the Italian environmental group Legambiente). These include trafficking in exotic animals and stolen timber, running illegal slaughterhouses and schemes to redirect water resources. An investigation led by the Sbarro Health Research Organization's President, Antonio Giordano, MD, PhD, found higher rates of cancers, cancer deaths and serious birth defects in areas where dumping had occurred. The findings were published in the journal Cancer Biology & Therapy last July. "There is no doubt," Giordano says, "that the waste dumped on farmland in the region going back at least to the 1970s is responsible for the higher tumor rates, birth defects and other health problems in a region long known for its fertile pastures and healthy people."

The Mystery of the 2012 Flu Season: Where are the Sick People?

January 26, 2012

An article in the Daily Beast asks: If this is flu season, why is no one getting sick? The commentary notes that while people should be "hacking and sneezing and aching" the Center for Disease Control and Prevention reports that the flu is at "relatively low" levels as of January 2012.

Scriptaid Effects on Cancer Cell Lines

January 16, 2012

Although endocrine therapy for breast cancer has shown excellent results in controlling
the disease, responsiveness to the therapy depends on whether or not there is expression of estrogen receptors in breast cancer cells. Research from the Sbarro Institute for Cancer Research and Molecular Medicine reports on the effectiveness of a new molecule, Scriptaid, that restores receptivity to endocrine therapy in breast cancer cell lines that had tested negative for the expression of estrogen receptors. The findings are reported in the Journal of Cellular Physiology.

Grant Helps Build NeuroAIDS  Research Capacity at Temple University School of Medicine

January 11, 2012

The National Institute of Mental Health (NIMH) has awarded Temple University a five-year, $8.34 million grant to create a Comprehensive NeuroAIDS Core Center (CNAC) at the School of Medicine.

The new center, one of only nine funded by NIMH, will enable researchers to study basic science and clinical aspects of HIV-induced neurological diseases and neurocognitive disorders. Kamel Khalili, Laura H. Carnell Professor and chair of neuroscience, is the principal investigator on the project.

 

Study Links Birth Defects in Fallujah to U.S. Assaults

January 4, 2012

A dramatic spike in birth defects in the Iraqi city of Fallujah may be caused by genetic damage  from weaponry used in American assaults that took place six years ago, according to a study published in the International Journal of Environmental Research and Public Health.

Novel Evidence Links Pretreatment Fasting Glucose to Slowed Cancer Progression

December 6, 2011

Researchers from the Sbarro Institute for Cancer Research and Molecular Medicine and the Human Health Foundation report that in a multidisciplinary study of 420 non-diabetic, breast and metastatic colorectal cancer patients treated with targeted agents, lower levels of pretreatment fasting glucose were predictive of longer times to disease progression.

Such evidence was particularly significant in breast cancer patients, according to results published in the Annals of Oncology.

Medicare To Cover Obesity Prevention Services

">December 2, 2011

Obese patients will now be eligible for fully paid screening and weight loss counseling sessions under Medicare, the Centers for Medicare and Medicaid Services announced.

"I believe this is a great development that should set policy basis for other insurance providers. Innovative counseling programs will likely enhance still insufficient awareness about obesity and its serious health consequences," said Dr. Eva Surmacz, Associate Professor in Biology (Adjunct) and director of the Obesity and Cancer Program at the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University’s College of Science and Technology.

 


 

 






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