SALUTE PRESS NEWS
His Excellency Claudio Bisogniero, Italian Ambassador
to the United States, will visit Temple's Sbarro Institute for Cancer Research and Molecular
May 16th, 2013
On Friday, May 17, 2013, at 10:30 AM, His Excellency Claudio
Bisogniero, Italian Ambassador to the United States will
visit Temple to honor the excellence in American-Italian research collaboration as exemplified
by the Sbarro
Institute at Temple. He will be joined in his tour by Temple President Neil Theobold,
Provost Hai-Lung Dai, College of Science and Technology Dean Michael Klein and Sbarro
Director Antonio Giordano.
For more information please see this Temple News Release .
The Power of Cocoa Polyphenols Against Neurodegenerative Diseases
April 11th, 2013
Epidemiological studies have indicated that dietary habits and antioxidants from
diet can influence the incidence of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Now,
a new study from the Sbarro Health Research Organization (SHRO), Center for Biotechnology, Temple University,
Philadelphia PA and Lombardi Cancer Center , Georgetown University Washington DC (USA) , University of
University of L'Aquila (Italy) and University of Siena (Italy) shows that cocoa polyphenols triggers neuroprotection
by activating BDNF survival pathway, both on Aβ plaque treated cells and on Aβ oligomers treated cells,
resulting in the counteraction of neurite dystrophy,
For more information please see this Newswise article .
Important International Study on the Link Between Obesity and Breast Cancer
April 3rd, 2013
The link between obesity and cancer seems now well established although the
molecular mechanisms underlying this connection are still largely unexplored. A group of researchers in
Italy led by Antonio Giordano, M.D., Ph.D., the Founder and Director of the Sbarro Institute for Cancer Research and
Molecular Medicine, and Center of Biotechnology, College of Science and Technology of the Temple University in
Philadelphia, has studied the correlation between breast cancer and insulin resistance - an obesity-related condition
in which certain cells fail to respond to the glucose-lowering action of the insulin hormone.
Their findings appear in the Journal of Experimental and Clinical Cancer Research.
For more information please see this Newswise article .
Pfizer CDK Inhibitor and Cancer Progression
March 16th, 2013
Data from a recent clinical study by Pfiezer has renewed interest
in CDK inhibitors to block the progress of Cancer. The concept was featured in a
Nature Biotechnology article.
"The main issue is to understand which CDKs should be targeted in specific cancers where they have a key role in the
oncogenic process" stated Dr. Antonio Giordano of the Sbarro Institute for Cancer Research and Molecular Medicine,
Temple University in Philadelphia. Dr. Giordano was the first to discover CDK9 and to describe a link between
cyclins/CDKs and tumorigenesis.
For more information please see this
Increased Incidence of Breast Cancer in Italy
November 30th, 2012
A new study on the incidence of breast cancer in Italy has been
published in the
International Journal of Experimental and Clinical Cancer Research. The authors
belong to a multidisciplinary Italian-American team led by Prof. Antonio Giordano, Director of the
Sbarro Institute for Cancer Research and Molecular Medicine College of Science and Technology
Temple University of Philadelphia, USA.
"Cancer is also a matter of numbers," says Giordano, internationally renowned oncologist engaged for
years in the fight against cancer, who recently launched an appeal - signed by over 500 researchers -
to protect the environment from the irresponsible dumping of toxic wastes, carcinogenic waste. "The
identification of the precise number of cancer cases at a population level and by geographical area is
crucial to orient public health strategies towards cancer prevention and early diagnosis."
SHRO Press Release
For more information please see the interview with Dr. Giordano and this
Dr. Giordano receives International Award
November 13th, 2012
Antonio Giordano, M.D., Ph.D. is being awarded the Grande Ippocrate Award for Scientific
Research and Communication. The award ceremony will take place at the "Castel Nuovo"on November 19, 2012.
Conference on Breast Cancer: Bridging Research and Clinical Medicine
October 6th, 2012
On October 12, 2012, from 2:00 to 4:00 p.m., the Sbarro Health Research Organization,
Inc. (S.H.R.O.), the Giovan Giacomo Giordano Foundation, the College of Science and Technology at Temple University and
the National Italian American Foundation (NIAF) (www.niaf.org) will jointly present the "Conference on Breast Cancer:
Bridging Research and Clinical Medicine" on the occasion of NIAF's 37th anniversary gala weekend at the Hilton Hotel
in Washington, D.C.
SHRO Press Release
Toxic Dumping in Naples Leads to Increased Cancer Rates in Naples
August 21st, 2012
On July the 30th, the Pascale National Cancer Institute of Naples made a shocking
report: 47% more people are stricken with cancer in Naples than in the rest of the Italy.
SHRO Press Release
New Properties of Stem Cells via Simulated Microgravity
July 5th, 2012
A recent study led by Andrew Puca, Ph.D. under the supervision and direction of
Antonio Giordano, M.D., Ph.D. set out to illustrate novel mechanical transduction properties of Hematopoietic Stem
Cells in relation to defining the expression of humoral factors by facilitating paracrine/autocrine signalling via
Rest of NewsWise Press Release
S.H.R.O. hosts free seminar on commercialization of science.
June 1, 2012
S.H.R.O., in collaboration with Temple University's College of Science & Technology, the
Italian Trade Commission and Innova Consulting Group, will host a seminar that aims to provide concrete tools and
examples to support the commercialization of science research by creating start-ups.
"The Price of a False Idea about Economic Growth:
Health Research Cuts and Uncontrolled Toxic Agents"
May 9, 2012
In this new essay, Philosopher Sheldon W. Samuels takes us to the
heart of the budget and regulatory battles that engulf the courts, congress and administration to
explain the long history resulting in the sidelining of
disease prevention and obstruction in controlling environmental threats to human life.
Novel Mechanism May Lead to New Targeted Pharmacological Cancer Treatment
April 24, 2012
In a new study from the Sbarro Health Research Organization, Flavio Rizzolio shows
that Pin1 (protein interacting with NIMA (never in mitosis A)-1), a peptidylprolyl isomerase involved in the
control of protein phosphorylation, is an essential mediator for inactivation of the pRB. The findings,
published in Cell Death and Differentiation, have important implications for cancer treatment.
Temple News Release Abstract in PubMed
Rules For Living better
March 28, 2012
This article, published in Italian in the online journal La Gazzetta Gastronomica,
outlines eight simple rules that the World Cancer Research Fund recommends for achieving a healthy lifestyle.
Italy's Eco Mafia.
Mafia Are Cashing In On Toxic Dumping and Other Environmental Crimes.
March 28, 2012
Christine MacDonald's article published in E Magazine (March/April 2012) discusses
how the Mafia has continued to commit atrocious environmental crimes (more than 30,000 in 2010 in Italy alone,
according to the Italian environmental group Legambiente). These include trafficking in exotic animals and stolen
timber, running illegal slaughterhouses and schemes to redirect water resources. An investigation led by the
Sbarro Health Research Organization's President, Antonio Giordano, MD, PhD, found higher rates of cancers,
cancer deaths and serious birth defects in areas where dumping had occurred. The findings were published in the
journal Cancer Biology & Therapy last July. "There is no doubt," Giordano says, "that the waste dumped on
farmland in the region going back at least to the 1970s is responsible for the higher tumor rates, birth defects
and other health problems in a region long known for its fertile pastures and healthy people."
The Mystery of the 2012 Flu Season: Where are the Sick People?
January 26, 2012
An article in the
Daily Beast asks: If this is flu season, why is no one getting sick? The commentary notes that while people should be "hacking and sneezing and aching" the Center for Disease Control and Prevention reports that the flu is at "relatively low" levels as of January 2012.
Scriptaid Effects on Cancer Cell Lines
January 16, 2012
Although endocrine therapy for breast cancer has shown excellent results in controlling
the disease, responsiveness to the therapy depends on whether or not there is expression of estrogen receptors in breast cancer cells. Research from the Sbarro Institute for Cancer Research and Molecular Medicine reports on the effectiveness of a new molecule, Scriptaid, that restores receptivity to endocrine therapy in breast cancer cell lines that had tested negative for the expression of estrogen receptors. The findings are reported in the J ournal of Cellular Physiology.
Grant Helps Build NeuroAIDS Research Capacity at Temple University School of Medicine
January 11, 2012
The National Institute of Mental Health (NIMH) has awarded Temple University a five-year, $8.34 million grant to create a Comprehensive NeuroAIDS Core Center (CNAC) at the School of Medicine.
The new center, one of only nine funded by NIMH, will enable researchers to study basic science and clinical aspects of HIV-induced neurological diseases and neurocognitive disorders. Kamel Khalili, Laura H. Carnell Professor and chair of neuroscience, is the principal investigator on the project.
Study Links Birth Defects in Fallujah to U.S. Assaults
January 4, 2012
A dramatic spike in birth defects in the Iraqi city of Fallujah may be caused by genetic damage from weaponry used in American assaults that took place six years ago, according to a study published in the International Journal of Environmental Research and Public Health.
Novel Evidence Links Pretreatment Fasting Glucose to Slowed Cancer Progression
December 6, 2011
Researchers from the Sbarro Institute for Cancer Research and Molecular Medicine and the Human Health Foundation report that in a multidisciplinary study of 420 non-diabetic, breast and metastatic colorectal cancer patients treated with targeted agents, lower levels of pretreatment fasting glucose were predictive of longer times to disease progression.
Such evidence was particularly significant in breast cancer patients, according to results published in the A
nnals of Oncology.
Medicare To Cover Obesity Prevention Services
">December 2, 2011
Obese patients will now be eligible for fully paid screening and weight loss counseling sessions under Medicare, the Centers for Medicare and Medicaid Services announced.
"I believe this is a great development that should set policy
basis for other insurance providers. Innovative counseling programs will likely enhance still
insufficient awareness about obesity and its serious health consequences," said Dr. Eva
Surmacz, Associate Professor in Biology (Adjunct) and director of the Obesity and Cancer Program at
the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University’s College
of Science and Technology.
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