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Administration |
Antonio Giordano, M.D., Ph.D. Antonio Giordano, M.D., Ph.D., President and Chairman of the Board of the Sbarro Health Research Organization, Director of the Sbarro Institute for Cancer Research and Molecular Medicine and Co-Director of the Center of Biotechnology at Temple University's College of Science and Technology has been an internationally recognized researcher specializing in the genetics of cancer and gene therapy for twenty years. At 26, while a post-doctoral fellow at Cold Spring Harbor Laboratory in New York, Dr. Giordano discovered the protein cyclone A, a substance that regulates growth in the cell cycle. At Temple University, he discovered Rb2/p130, a tumor suppressor gene which has since been found to be active in lung, endometrial, brain, breast, liver and ovarian cancers, and CDK9 and CDK10, guardians of the human genome. Research has subsequently shown that CDk9 plays a critical role in cell differentiation, particularly in muscles; HIV transcription; and the inception of tumors. |
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Italiano
English |
But Dr. Giordano has not limited his activities to the lab. Recognizing that scientists often make their most exciting discoveries while they are young, in 1993, while at Thomas Jefferson University, he founded the Sbarro Institute for Cancer Research and Molecular Medicine with the generous help of Mario Sbarro, president of Sbarro, Inc., an internationally successful restaurant chain. In 2002, the Institute forged an exciting alliance with Temple University, forming the Sbarro Health Research Organization (SHRO). Under the agreement, funds from SHRO go directly to the Sbarro Institute for Cancer Research and Molecular Medicine at Temple, where promising researchers from around the globe pursue ground-breaking research in the molecular workings of cancer and other devastating diseases. The agreement with Temple was renewed in 2005, with the addition of two new research programs in molecular therapeutics and the study of the connections between obesity and cancer. A native of Naples, Italy, Dr. Giordano earned his medical degree summa cum laude from the University of Naples in 1986 and his doctorate in pathology summa cum laude from the University of Trieste Medical School in 1990. He was a post-doctoral fellow in the department of microbiology and immunology at New York Medical College in Valhalla (N.Y.) from 1987 to 1988. From 1988 to 1992, he was a post-doctoral fellow at Cold Spring Harbor Laboratory (N.Y), which was led by James Watson, the co-discoverer of DNA structure and the father of modern genetics. Since 1992, Giordano has been awarded nine patents, with six pending. He has published over two hundred papers on his work in the fields of cell cycles, gene therapy and the genetics of cancer and serves on the editorial of a number of professional journals. His work is funded by National Institutes of Health (NIH) grants, as well as individual and program project grants from SHRO. He has received a number of international awards for his work in cancer research. Dr. Giordano serves on the editorial board of numerous leading professional journals, including Frontiers in Bioscience, Cancer Biology and Therapy, the Journal of Cellular Biochemistry and the Journal of Cellular Physiology, of which he is Editor and Reviews Editor. Other professional activities include grant reviewer for the American Cancer Society and the NIH's National Cancer Institute, external reviewer for evaluating research programs for the U.S. Food and Drug Administration, and ad hoc reviewer for National Science Foundation and Veterans Administration grant programs. Over the past ten years, Dr. Giordano has been an invited lecturer at more than 200 scientific meetings throughout the United States and abroad. In addition to his work with the Sbarro Institute for Cancer Research and Molecular Medicine, Dr. Giordano has been appointed chiara fama Professor of Pathology at the University of Siena, and has trained more than 130 scientists and physician investigators from all over the world. Dr. Giordano and his wife, Dr. Mina Massaro, Assistant Professor of Ophthalmology at the Scheie Eye Institute of the University of Pennsylvania, live in Radnor, Pennsylvania, USA. They have three children: Maria Teresa, Giovan Giacomo and Luca. |
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© Copyright 2003, Sbarro Health Research Organization,All rights reserved. |